Wednesday, March 2, 2011

Introduction of Structure

Triose Phosphate Isomerase     a.k.a TIM


  1. Very nice enzyme! I have a few suggestions:
    1) it looks like your file sizes are quite small--the pictures will be even better if you can save the images when they are larger. Or did you use screen capture?
    2) have you thought of incorporating this clip?

  2. Hi, Stacey! I found this blog because I was looking for images of TIM (I'm doing a series of cartoons about glycolysis, and one of the ways it occurred to me to distinguish one enzyme from another in a memorable fashion was to give them a cartoon shape based loosely on their actual structure -- like, hexokinase somewhat resembles Pac-Man, phosphoglucose isomerase looks like a pair of interlocked hands, phosphofructokinase looks like a pinwheel and aldolase looks like a butterfly -- that's all I have so far) and clicking on one of the images that looked promising in terms of showing the whole protein (rather than just the active site) led me here.

    Anyway, I just wanted to tell you this a really cool blog! I don't know if you still look at it anymore, but I'll leave this comment anyway.

  3. the difference in inner energy between isomers. Isomers having similar energy levels can interconvert readily and are usually detected in comparable proportions. Isomerases can lower the isomerization energy and thus increase the reaction rate. isomerase introduction